Hi @sammecooper! As I'm sure you know, the higher the Keyword Difficulty Score, the harder the keyword will be to rank for. A higher DA does correlate with a higher likelihood to rank BUT when using DA, it's important that you are comparing your site to your true search competitors— sites w/in the same category and of the same caliber. We actually have a video that explains this in more detail if that helps. https://moz.rankious.com/_moz/learn/seo/domain-authority
Personally, I'm a fan of going for low-hanging fruit first: keywords that have lower difficulty and still have decent value. Then, once you've tackled these, you can aim for those harder ones. We have a great resource all about keyword research, The SEO Keyword Research Master Guide that may help you in your quest for keyword gems.