In this case, we can see that our highest volume keywords have a Keyword Difficulty score no greater than 57.
This means that keywords above this score will likely be difficult for us to rank for, and keywords below this score may be a little easier.
If your site is completely brand new, you may find that ranking for even the easiest of keywords (with scores in the 20s and 30s) is still very, very difficult.
B. Topical relevance
The Keyword Difficulty score is meant to apply to the "average" site, but your site isn't average. Your site is about something: a topic. And what that topic is about can determine how easy (or hard) it is to rank for a new term.
Closely related topics are typically easier to rank for. For example, if you rank for "wholesale motorcycle gloves", it's likely easier to rank for "wholesale motorcycle helmets".
Conversely, if the target keyword is way outside your normally-ranking topics, then the keyword is likely harder for you to rank for. For example, if we here at Moz tried to rank for "motorcycle helmets", we might have a hard time doing so.